DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF AMLODIPINE BESYLATE, OLMESARTAN MEDOXOMIL AND HYDROCHLORTHIAZIDE IN TABLET DOSAGE FORM
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چکیده
منابع مشابه
Development and Validation of Rp-hplc Method for Simultaneous Estimation of Lisinopril and Amlodipine Besylate in Tablet Dosage Form
A simple, specific, precise, and accurate reversed-phase HPLC method was developed and validated for simultaneous estimation of lisinopril and amlodipine besylate in tablet dosage forms. The separation was achieved by Hypersil ODS-BP C18 column (250 mm × 4.6 mm; 5.0 μm) using methanol: phosphate buffer at pH 6 adjusted with orthophosphoric acid (30: 70, v/v) as eluent, at a flow rate of 1 mL/mi...
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In the present work for the determination of Olmesartan Medoxomil, Hydrochlorothiazide and Amlodipine a simple, rapid and precise high performance liquid chromatography procedure has been developed and validated. The separation and quantification were achieved on a Cyano C18 column using a mobile phase of filtered and degassed mixture of buffer and acetonitrile in the ratio of 830:170 with of a...
متن کاملStability-indicating method for simultaneous estimation of olmesartan medoxomile, amlodipine besylate and hydrochlorothiazide by RP-HPLC in tablet dosage form.
A simple, specific, accurate and precise stability-indicating reversed-phase high-performance liquid chromatographic method was developed for simultaneous estimation of olmesartan medoxomile (OLME), amlodipine besylate (AMLO) and hydrochlorothiazide (HCTZ) in tablet dosage form. The method was developed using an RP C18 base deactivated silica column (250 × 4.6 mm, 5 µm) with a mobile phase cons...
متن کاملSIMULTANEOUS ESTIMATION OF AMLODIPINE BESYLATE AND HYDROCHLORTHIAZIDE IN TABLET DOSAGE FORM BY RP-HPLC M.V.Kumudhavalli*, K.Anand babu, B.Jayakar
A simple, precise, rapid and accurate RP-HPLC method has been developed for the simultaneous estimation of Amlodipine besylate and Hydrochlorthiazide in tablet formulations. The chromatographic separation was achieved on a Shimadzu Symmetry C18 column (250 mm x 4.6mm, 5.0 μ particle size) using Methanol: Acetonitrile: 50mM Na2HPO4 pH7.0 (60:20:20v/v/v) with 1% triethylamine. Flow rate was 1ml/m...
متن کاملDevelopment and Validation of RP-HPLC Method for Simultaneous Estimation of Enalapril Maleate and Amlodipine Besylate in Combined Dosage form
Article history: Received on: 08/09/2012 Revised on: 19/09/2012 Accepted on: 24/09/2012 Available online: 28/09/2012 A simple, precise and rapid reverse-phase HPLC method has been developed and subsequently validated for the simultaneous estimation of Amlodipine besylate and Enalapril maleate from their combination drug product. The proposed RP-HPLC method utilizes a Phenomenex C18, 5 μm, 250 m...
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ژورنال
عنوان ژورنال: International Journal of Research in Ayurveda & Pharmacy
سال: 2014
ISSN: 2277-4343
DOI: 10.7897/2277-4343.054106